VEGFA Rabbit Monoclonal Antibody [Clone ID: R04-6D7]
Supplier Origene
Swiss-Prot Acc.P15692.Growth factor active in angiogenesis, vasculogenesis and endothelial cell growth. Induces endothelial cell proliferation, promotes cell migration, inhibits apoptosis and induces permeabilization of blood vessels. Binds to the FLT1/VEGFR1 and KDR/VEGFR2 receptors, heparan sulfate and heparin. NRP1/Neuropilin-1 binds isoforms VEGF-165 and VEGF-145. Isoform VEGF165B binds to KDR but does not activate downstream signaling pathways, does not activate angiogenesis and inhibits tumor growth. Binding to NRP1 receptor initiates a signaling pathway needed for motor neuron axon guidance and cell body migration, including for the caudal migration of facial motor neurons from rhombomere 4 to rhombomere 6 during embryonic development .
- Protein names Vascular endothelial growth factor A
- Protein alternative names Vascular permeability factor, , , ,
- Conjugate/tag Unconjugated
- Catalog Number TA385548
- Isotype IgG
- Storage format 50mM Tris-Glycine(pH 7.4), 0.15M NaCl, 40% Glycerol, 0.01% Sodium azide and 0.05% BSA
- Clonality Monoclonal
- Accession numbers P15692
- Gene target VEGFA
- Clone R04
- Datasheet https://cdn.origene.com/datasheet/ta385548.pdf
- MSDS https://cdn.origene.com/sds/ta385548.pdf
- Shipping handling time 28 days