American Research Products

TTR Monoclonal Antibody

Supplier American Research Products

$179.00 / 60 ul
$279.00 / 120 ul
$449.00 / 200 ul
Applications : Western Blot / Immunohistochemistry
Reactivity : Human
Host: : Mouse

This gene encodes transthyretin, one of the three prealbumins including alpha-1-antitrypsin, transthyretin and orosomucoid. Transthyretin is a carrier protein; it transports thyroid hormones in the plasma and cerebrospinal fluid, and also transports retinol (vitamin A) in the plasma. The protein consists of a tetramer of identical subunits. More than 80 different mutations in this gene have been reported; most mutations are related to amyloid deposition, affecting predominantly peripheral nerve and/or the heart, and a small portion of the gene mutations is non-amyloidogenic. The diseases caused by mutations include amyloidotic polyneuropathy, euthyroid hyperthyroxinaemia, amyloidotic vitreous opacities, cardiomyopathy, oculoleptomeningeal amyloidosis, meningocerebrovascular amyloidosis, carpal tunnel syndrome, etc.

  • Protein names Transthyretin
  • Protein alternative names ATTR, Prealbumin, TBPA, ,
  • Immunogen Recombinant Protein of TTR
  • Antibody type Primary Antibody
  • Catalog Number E-AB-22144
  • Isotype IgG
  • Clonality Monoclonal
  • Accession numbers P02766
  • Gene target TTR
  • Clone 2A4

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