Origene

RUNX1T1 Mouse Monoclonal Antibody [Clone ID: OTI1H1]

Supplier Origene

$216.68 / 30 ul
Applications : Immunofluorescence / Western Blot
Reactivity : Mouse / Human / Rat
Conjugate/Tag : Unconjugated
Host: : Mouse

This gene encodes a member of the myeloid translocation gene family which interact with DNA-bound transcription factors and recruit a range of corepressors to facilitate transcriptional repression. The t(8;21)(q22;q22) translocation is one of the most frequent karyotypic abnormalities in acute myeloid leukemia. The translocation produces a chimeric gene made up of the 5'-region of the runt-related transcription factor 1 gene fused to the 3'-region of this gene. The chimeric protein is thought to associate with the nuclear corepressor/histone deacetylase complex to block hematopoietic differentiation. Alternative splicing results in multiple transcript variants. [provided by RefSeq]

  • Protein names Protein CBFA2T1
  • Protein alternative names Cyclin-D-related protein, Eight twenty one protein, Protein ETO, Protein MTG8, Zinc finger MYND domain-containing protein 2
  • Conjugate/tag Unconjugated
  • Catalog Number TA504703S
  • Isotype IgG1
  • Storage format PBS (PH 7.3) containing 1% BSA, 50% glycerol and 0.02% sodium azide.
  • Clonality Monoclonal
  • Accession numbers Q06455
  • Gene target RUNX1T1
  • Clone OTI1H1
  • Datasheet https://cdn.origene.com/datasheet/ta504703s.pdf
  • MSDS https://cdn.origene.com/sds/ta504703s.pdf
  • Shipping handling time 0 days

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