PTPN1 Monoclonal Antibody (OTI1A2), TrueMAB™

Supplier Thermo fisher

$416.51 / 100 ul
Applications : Western Blot / Flow Cytometry / Immunocytochemistry
Reactivity : Human
Conjugate/Tag : Unconjugated
Host: : Mouse

Target Information

PTP1B (PTPN1) is a tyrosine-protein phosphatase which acts as a regulator of endoplasmic reticulum unfolded protein response. It mediates dephosphorylation of EIF2AK3/PERK and in turn inactivates the protein kinase activity of EIF2AK3/PERK. PTP1B also plays a role in CKII- and p60c-src-induced signal transduction cascades. It regulates the EFNA5-EPHA3 signaling pathway which modulates cell reorganization and cell-cell repulsion. PTP1B also regulates the hepatocyte growth factor receptor signaling pathway through dephosphorylation of MET.

  • Protein names Tyrosine-protein phosphatase non-receptor type 1
  • Protein alternative names Protein-tyrosine phosphatase 1B, , , ,
  • Immunogen Full length human recombinant protein of human PTPN1 produced in HEK293T cell.
  • Conjugate/tag Unconjugated
  • Antibody type Primary Antibody
  • Catalog Number TA503038
  • Isotype IgG2a
  • Storage format PBS with 1% BSA, 50% glycerol
  • Clonality Monoclonal
  • Accession numbers P18031
  • Gene target PTPN1
  • Clone OTI1A2
  • Datasheet

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