PTP1B Monoclonal Antibody (OTI1A2)
Supplier Thermo fisher
$560.59
/ 100 ul
Applications
:
Western Blot
/
Flow Cytometry
/
Immunocytochemistry
Reactivity
:
Human
Conjugate/Tag
:
Unconjugated
Host:
:
Mouse
Target Information
PTP1B (PTPN1) is a tyrosine-protein phosphatase which acts as a regulator of endoplasmic reticulum unfolded protein response. It mediates dephosphorylation of EIF2AK3/PERK and in turn inactivates the protein kinase activity of EIF2AK3/PERK. PTP1B also plays a role in CKII- and p60c-src-induced signal transduction cascades. It regulates the EFNA5-EPHA3 signaling pathway which modulates cell reorganization and cell-cell repulsion. PTP1B also regulates the hepatocyte growth factor receptor signaling pathway through dephosphorylation of MET.
- Protein names Tyrosine-protein phosphatase non-receptor type 1
- Protein alternative names Protein-tyrosine phosphatase 1B, , , ,
- Immunogen Full length human recombinant protein of PTPN1 produced in HEK293T cell
- Conjugate/tag Unconjugated
- Antibody type Primary Antibody
- Catalog Number MA5-25574
- Isotype IgG2a
- Storage format PBS, pH 7.3, with 1% BSA, 50% glycerol
- Clonality Monoclonal
- Accession numbers P18031
- Gene target PTPN1
- Clone OTI1A2
- Datasheet https://www.thermofisher.com/order/genome-database/dataSheetPdf?producttype=antibody&productsubtype=antibody_primary&productId=MA5-25574&version=302
