PSMB9 Monoclonal Antibody (OTI1D1)
Supplier Thermo fisher
Target Information
The proteasome is a multicatalytic proteinase complex with a highly ordered ring-shaped 20S core structure. The core structure is composed of 4 rings of 28 non-identical subunits; 2 rings are composed of 7 alpha subunits and 2 rings are composed of 7 beta subunits. Proteasomes are distributed throughout eukaryotic cells at a high concentration and cleave peptides in an ATP/ubiquitin-dependent process in a non-lysosomal pathway. An essential function of a modified proteasome, the immunoproteasome, is the processing of class I MHC peptides. This gene encodes a member of the proteasome B-type family, also known as the T1B family, that is a 20S core beta subunit. This gene is located in the class II region of the MHC in the immunoproteasome. Proteolytic processing is required to generate a mature subunit.
- Protein names Proteasome subunit beta type-9
- Protein alternative names Low molecular mass protein 2, Macropain chain 7, Multicatalytic endopeptidase complex chain 7, Proteasome chain 7, Proteasome subunit beta-1i
- Immunogen Human recombinant protein fragment corresponding to amino acids 21-219 of PSMB9 produced in E.coli
- Conjugate/tag Unconjugated
- Antibody type Primary Antibody
- Catalog Number MA5-25888
- Isotype IgG2a
- Storage format PBS, pH 7.3, with 1% BSA, 50% glycerol
- Clonality Monoclonal
- Accession numbers P28065
- Gene target PSMB9
- Clone OTI1D1
- Datasheet https://www.thermofisher.com/order/genome-database/dataSheetPdf?producttype=antibody&productsubtype=antibody_primary&productId=MA5-25888&version=316