PRMT7 Rabbit monoclonal antibody

Supplier Bioworld

$158.00 / 50 ul
$275.00 / 100 ul
Applications : Western Blot
Reactivity : Mouse / Rat / Human
Conjugate/Tag : Unconjugated
Host: : Rabbit

Protein arginine N-methyltransferase 7 (PRMT7) is a member of the protein arginine N-methyltransferase (PRMT) family of proteins that catalyze the transfer of a methyl group from S-adenosylmethionine (AdoMet) to a guanidine nitrogen of arginine . The three types of PRMTs share the ability to mono-methylate arginine residues, but vary in their ability to generate differential methylation states . Mono-methylated arginine residues are further methylated by type I PRMTs to generate an asymmetric di-methyl arginine or by type II PRMTs to form a symmetric-dimethyl arginine. Type III methyltransferases are only able to mono-methylate arginine residues . Research studies indicate that PRMT7 is a type III PRMT that displays substrate specificity for an arginine-X-arginine (RXR) motif surrounded by several basic residues . PRMT7 interacts with a wide array of protein substrates and likely plays a role in many biological processes including pluripotency, neuronal differentiation, genomic instability, snRNP biogenesis, and breast cancer metastasis .

  • Protein names Protein arginine N-methyltransferase 7
  • Protein alternative names Histone-arginine N-methyltransferase PRMT7, [Myelin basic protein]-arginine N-methyltransferase PRMT7, , ,
  • Immunogen A synthetic peptide of human PRMT7
  • Conjugate/tag Unconjugated
  • Antibody type Primary Antibody
  • Catalog Number MB66380
  • Clonality Monoclonal
  • Accession numbers Q9NVM4
  • Gene target PRMT7
  • Datasheet
  • MSDS

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