p53 Antibody / TP53 [clone TP53/1739] (V3952)

Supplier NSJ Bioreagents

$499.00 / 100 ug
$219.00 / 20 ug
$499.00 / 100 ug
Applications : Western Blot / Immunohistochemistry
Reactivity : Human
Host: : Mouse

Recognizes a 67kDa transmembrane protein, which is identified as CD5. The CD5 antigen is found on 95% of thymocytes and 72% of peripheral blood lymphocytes. In lymph nodes, the main reactivity is observed in T cell areas. Anti-CD5 is a pan T-cell marker that also reacts with a range of neoplastic B-cells, e.g. chronic lymphocytic leukemia/small lymphocytic lymphoma (CLL/SLL), mantle cell lymphoma, and a subset (~10%) of diffuse large B-cell lymphoma. CD5 aberrant expression is useful in making a diagnosis of mature T-cell neoplasms. Anti-CD5 detection is diagnostic in CLL/SLL within a panel of other B-cell markers, especially one that includes anti-CD23. Anti-CD5 is also very useful in differentiating among mature small lymphoid cell malignancies. In addition, anti-CD5 can be used in distinguishing thymic carcinoma (+) from thymoma (-). Anti-CD5 does not react with granulocytes or monocytes.

  • Protein names Cellular tumor antigen p53
  • Protein alternative names Antigen NY-CO-13, Phosphoprotein p53, Tumor suppressor p53, ,
  • Immunogen Recombinant full length human protein was used as the immunogen for the p53 antibody.
  • Antibody type Primary Antibody
  • Catalog Number V3952-100UG
  • Isotype IgG2a kappa
  • Clonality Monoclonal
  • Accession numbers P04637
  • Gene target TP53
  • Shipping handling time 1 days

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