p38 (MAPK14) Rabbit Monoclonal Antibody [Clone ID: R06-7D3]

Supplier Origene

$413.25 / 100 ul
Applications : Western Blot / Immunoprecipitation
Reactivity : Human
Conjugate/Tag : Unconjugated
Host: : Rabbit

The protein encoded by this gene is a member of the MAP kinase family. MAP kinases act as an integration point for multiple biochemical signals, and are involved in a wide variety of cellular processes such as proliferation, differentiation, transcription regulation and development. This kinase is activated by various environmental stresses and proinflammatory cytokines. The activation requires its phosphorylation by MAP kinase kinases (MKKs), or its autophosphorylation triggered by the interaction of MAP3K7IP1/TAB1 protein with this kinase. The substrates of this kinase include transcription regulator ATF2, MEF2C, and MAX, cell cycle regulator CDC25B, and tumor suppressor p53, which suggest the roles of this kinase in stress related transcription and cell cycle regulation, as well as in genotoxic stress response. Four alternatively spliced transcript variants of this gene encoding distinct isoforms have been reported. [provided by RefSeq, Jul 2008]

  • Protein names Mitogen-activated protein kinase 14
  • Protein alternative names Cytokine suppressive anti-inflammatory drug-binding protein, MAP kinase MXI2, MAX-interacting protein 2, Mitogen-activated protein kinase p38 alpha, Stress-activated protein kinase 2a
  • Conjugate/tag Unconjugated
  • Catalog Number TA384730
  • Isotype IgG
  • Storage format 50mM Tris-Glycine(pH 7.4), 0.15M NaCl, 40% Glycerol, 0.01% Sodium azide and 0.05% BSA
  • Clonality Monoclonal
  • Accession numbers Q16539
  • Gene target MAPK14
  • Clone R06
  • Datasheet https://cdn.origene.com/datasheet/ta384730.pdf
  • MSDS https://cdn.origene.com/sds/ta384730.pdf
  • Shipping handling time 28 days

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