Nogo B receptor (NUS1) Rabbit Monoclonal Antibody [Clone ID: R01-3K8]

Supplier Origene

$413.25 / 100 ul
Applications : Western Blot
Reactivity : Mouse / Human / Rat
Conjugate/Tag : Unconjugated
Host: : Rabbit

Swiss-Prot Acc.Q96E22.With DHDDS, forms the dehydrodolichyl diphosphate synthase (DDS) complex, an essential component of the dolichol monophosphate (Dol-P) biosynthetic machinery. Both subunits contribute to enzymatic activity, i.e. condensation of multiple copies of isopentenyl pyrophosphate (IPP) to farnesyl pyrophosphate (FPP) to produce dehydrodolichyl diphosphate (Dedol-PP), a precursor of dolichol phosphate which is utilized as a sugar carrier in protein glycosylation in the endoplasmic reticulum (ER) (PubMed:21572394, PubMed:25066056, PubMed:28842490). Regulates the glycosylation and stability of nascent NPC2, thereby promoting trafficking of LDL-derived cholesterol. Acts as a specific receptor for the N-terminus of Nogo-B, a neural and cardiovascular regulator (PubMed:16835300).

  • Protein names Dehydrodolichyl diphosphate synthase complex subunit NUS1
  • Protein alternative names Cis-prenyltransferase subunit NgBR, Nogo-B receptor, Nuclear undecaprenyl pyrophosphate synthase 1 homolog, ,
  • Conjugate/tag Unconjugated
  • Catalog Number TA384884
  • Isotype IgG
  • Storage format 50mM Tris-Glycine(pH 7.4), 0.15M NaCl, 40% Glycerol, 0.01% Sodium azide and 0.05% BSA
  • Clonality Monoclonal
  • Accession numbers Q96E22
  • Clone R01
  • Datasheet https://cdn.origene.com/datasheet/ta384884.pdf
  • MSDS https://cdn.origene.com/sds/ta384884.pdf
  • Shipping handling time 28 days

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