NEK9 Monoclonal Antibody (OTI1H1), TrueMAB™

Supplier Thermo fisher

$419.35 / 100 ul
Applications : Western Blot / Flow Cytometry / Immunocytochemistry
Reactivity : Human
Conjugate/Tag : Unconjugated
Host: : Mouse

Target Information

NEK9, a NEK type protein kinase, regulates chromosome alignment and segregation in mitosis. The protein has a N-terminal NIMA-like catalytic domain, a central domain with homology to the guanine nucleotide exchange factor for the GTPase Ran (RCC1), and a C-terminal coiled-coil domain. It is phosphorylated by active p34(Cdc2) and is capable of autophosphorylation and oligomerization. The activated protein binds Nek6 and RCC1, and has been shown to associate with the human homolog of the Drosophila protein Bicaudal D (Bicd2) in vivo and to phosphorylate this coiled-coil protein in vitro. NEK9 expression has been documented in normal human brain. ESTs have been isolated from several tissue libraries, including normal bone, lymph and thymus and cancerous cervix, eye, lymph and placenta.

  • Protein names Serine/threonine-protein kinase Nek9
  • Protein alternative names Nercc1 kinase, Never in mitosis A-related kinase 9, NimA-related kinase 8, ,
  • Immunogen Full length human recombinant protein of human NEK9 produced in HEK293 cell.
  • Conjugate/tag Unconjugated
  • Antibody type Primary Antibody
  • Catalog Number TA503326
  • Isotype IgG1
  • Storage format PBS with 1% BSA, 50% glycerol
  • Clonality Monoclonal
  • Accession numbers Q8TD19
  • Gene target NEK9
  • Clone OTI1H1
  • Datasheet

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