Origene

MYBPC3 Mouse Monoclonal Antibody [Clone ID: OTI1H1]

Supplier Origene

$650.04 / 100 ug
Applications : ELISA
Reactivity : Human
Conjugate/Tag : Unconjugated
Host: : Mouse

MYBPC3 encodes the cardiac isoform of myosin-binding protein C. Myosin-binding protein C is a myosin-associated protein found in the cross-bridge-bearing zone (C region) of A bands in striated muscle. MYBPC3, the cardiac isoform, is expressed exclussively in heart muscle. Regulatory phosphorylation of the cardiac isoform in vivo by cAMP-dependent protein kinase (PKA) upon adrenergic stimulation may be linked to modulation of cardiac contraction. Mutations in MYBPC3 are one cause of familial hypertrophic cardiomyopathy. [provided by RefSeq, Jul 2008]

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