Mouse Anti Human TTR Monoclonal Clone 2A4 from Innovative Research is a monoclonal antibody in a liquid format, buffered in PBS with 0.02% sodium azide and 50% glycerol pH 7.4. This antibody has been purified using Protein A purification.More Details:This gene encodes transthyretin, one of the three prealbumins including alpha-1-antitrypsin, transthyretin and orosomucoid. Transthyretin is a carrier protein; it transports thyroid hormones in the plasma and cerebrospinal fluid, and also transports retinol (vitamin A) in the plasma. The protein consists of a tetramer of identical subunits. More than 80 different mutations in this gene have been reported; most mutations are related to amyloid deposition, affecting predominantly peripheral nerve and/or the heart, and a small portion of the gene mutations is non-amyloidogenic. The diseases caused by mutations include amyloidotic polyneuropathy, euthyroid hyperthyroxinaemia, amyloidotic vitreous opacities, cardiomyopathy, oculoleptomeningeal amyloidosis, meningocerebrovascular amyloidosis, carpal tunnel syndrome, etc.This product can be used in analytical tools such as Western Blot,IHC-p.At Innovative Research, we provide reliable, consistent products that deliver reliable, consistent results.For research use only.