KCTD21 Rabbit Monoclonal Antibody [Clone ID: R02-4B5]

Supplier Origene

$413.25 / 100 ul
Applications : Western Blot
Reactivity : Mouse / Human / Rat
Conjugate/Tag : Unconjugated
Host: : Rabbit

Swiss-Prot Acc.Q4G0X4.Probable substrate-specific adapter of a BCR (BTB-CUL3-RBX1) E3 ubiquitin-protein ligase complex mediating the ubiquitination and subsequent proteasomal degradation of target proteins. Promotes the ubiquitination of HDAC1. Can function as antagonist of the Hedgehog pathway by affecting the nuclear transfer of transcription factor GLI1; the function probably occurs via HDAC1 down-regulation, keeping GLI1 acetylated and inactive. Inhibits cell growth and tumorigenicity of medulloblastoma (MDB) (PubMed:21472142).

  • Protein names BTB/POZ domain-containing protein KCTD21
  • Protein alternative names KCASH2 protein, Potassium channel tetramerization domain-containing protein 21, , ,
  • Conjugate/tag Unconjugated
  • Catalog Number TA384589
  • Isotype IgG
  • Storage format 50mM Tris-Glycine(pH 7.4), 0.15M NaCl, 40% Glycerol, 0.01% Sodium azide and 0.05% BSA
  • Clonality Monoclonal
  • Accession numbers Q4G0X4
  • Clone R02
  • Datasheet https://cdn.origene.com/datasheet/ta384589.pdf
  • MSDS https://cdn.origene.com/sds/ta384589.pdf
  • Shipping handling time 28 days

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