Histone H3 (phospho-S10) polyclonal antibody

Supplier Bioworld

$168.00 / 50 ul
$298.00 / 100 ul
Applications : Immunofluorescence / Western Blot / Immunohistochemistry
Reactivity : Mouse / Rat / Human
Conjugate/Tag : Unconjugated
Host: : Rabbit

Histones are basic nuclear proteins that are responsible for the nucleosome structure of the chromosomal fiber in eukaryotes. Nucleosomes consist of approximately 146 bp of DNA wrapped around a histone octamer composed of pairs of each of the four core histones (H2A, H2B, H3, and H4). The chromatin fibre is further compacted through the interaction of a linker histone, H1, with the DNA between the nucleosomes to form higher order chromatin structures.Covalent modifications of the canonical core histones, including acetylation, phosphorylation, methylation, and monoubiquitination are used to mark nucleosomes to create chromatin domains with a range of functions.

  • Protein names Histone H3.1, Histone H3.3, Histone H3.2
  • Protein alternative names Histone H3/a, Histone H3/b, Histone H3/c, Histone H3/d, Histone H3/f, , , , , , H3-clustered histone 13, H3-clustered histone 14, H3-clustered histone 15, Histone H3/m, Histone H3/o
  • Immunogen Synthetic phosphopeptide derived from human Histone H3 around the phosphorylation site of Serine 10.
  • Conjugate/tag Unconjugated
  • Antibody type Primary Antibody
  • Catalog Number BS4094
  • Isotype IgG
  • Clonality Polyclonal
  • Accession numbers P68431 Q71DI3 P84243
  • Gene target H31
  • Datasheet http://www.bioworlde.com/pdf/BS4094.pdf
  • MSDS http://www.bioworlde.com/MSDS/MSDS.pdf

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