GDF15 Rabbit Monoclonal Antibody [Clone ID: R04-8I1]
Supplier Origene
$416.06
/ 100 ul
Swiss-Prot Acc.Q99988.Regulates food intake, energy expenditure and body weight in response to metabolic and toxin-induced stresses (PubMed:28953886, PubMed:28846097, PubMed:28846098, PubMed:28846099, PubMed:23468844, PubMed:29046435). Binds to its receptor, GFRAL, and activates GFRAL-expressing neurons localized in the area postrema and nucleus tractus solitarius of the brainstem (PubMed:28953886, PubMed:28846097, PubMed:28846098, PubMed:28846099). It then triggers the activation of neurons localized within the parabrachial nucleus and central amygdala, which contitutes part of the 'emergency circuit' that shapes feeding responses to stressful conditions (PubMed:28953886). On hepatocytes, inhibits growth hormone signaling .
- Protein names Growth/differentiation factor 15
- Protein alternative names Macrophage inhibitory cytokine 1, NSAID-activated gene 1 protein, NSAID-regulated gene 1 protein, Placental TGF-beta, Placental bone morphogenetic protein
- Conjugate/tag Unconjugated
- Catalog Number TA384293
- Isotype IgG
- Storage format 50mM Tris-Glycine(pH 7.4), 0.15M NaCl, 40% Glycerol, 0.01% Sodium azide and 0.05% BSA
- Clonality Monoclonal
- Accession numbers Q99988
- Clone R04
- Datasheet https://cdn.origene.com/datasheet/ta384293.pdf
- MSDS https://cdn.origene.com/sds/ta384293.pdf
- Shipping handling time 28 days
