GABARAPL2 Rabbit Monoclonal Antibody [Clone ID: R03-7J2]
Supplier Origene
Applications
:
Western Blot
Reactivity
:
Human
/
Rat
Conjugate/Tag
:
Unconjugated
Host:
:
Rabbit
Swiss-Prot Acc.P60520.Ubiquitin-like modifier involved in intra-Golgi traffic. Modulates intra-Golgi transport through coupling between NSF activity and SNAREs activation. It first stimulates the ATPase activity of NSF which in turn stimulates the association with GOSR1 . Involved in autophagy. Plays a role in mitophagy which contributes to regulate mitochondrial quantity and quality by eliminating the mitochondria to a basal level to fulfill cellular energy requirements and preventing excess ROS production. Whereas LC3s are involved in elongation of the phagophore membrane, the GABARAP/GATE-16 subfamily is essential for a later stage in autophagosome maturation.
- Protein names Gamma-aminobutyric acid receptor-associated protein-like 2
- Protein alternative names GABA(A) receptor-associated protein-like 2, Ganglioside expression factor 2, General protein transport factor p16, Golgi-associated ATPase enhancer of 16 kDa, MAP1 light chain 3-related protein
- Conjugate/tag Unconjugated
- Catalog Number TA384278
- Isotype IgG
- Storage format 50mM Tris-Glycine(pH 7.4), 0.15M NaCl, 40% Glycerol, 0.01% Sodium azide and 0.05% BSA
- Clonality Monoclonal
- Accession numbers P60520
- Clone R03
- Datasheet https://cdn.origene.com/datasheet/ta384278.pdf
- MSDS https://cdn.origene.com/sds/ta384278.pdf
- Shipping handling time 28 days