COX2 (PTGS2) Rabbit Monoclonal Antibody [Clone ID: R04-3I1]

Supplier Origene

$413.25 / 100 ul
Applications : Western Blot / Immunohistochemistry
Reactivity : Mouse / Human / Rat
Conjugate/Tag : Unconjugated
Host: : Rabbit

Swiss-Prot Acc.P35354.Converts arachidonate to prostaglandin H2 (PGH2), a committed step in prostanoid synthesis (PubMed:26859324, PubMed:27226593). Constitutively expressed in some tissues in physiological conditions, such as the endothelium, kidney and brain, and in pathological conditions, such as in cancer. PTGS2 is responsible for production of inflammatory prostaglandins. Up-regulation of PTGS2 is also associated with increased cell adhesion, phenotypic changes, resistance to apoptosis and tumor angiogenesis. In cancer cells, PTGS2 is a key step in the production of prostaglandin E2 (PGE2), which plays important roles in modulating motility, proliferation and resistance to apoptosis.

  • Protein names Prostaglandin G/H synthase 2
  • Protein alternative names Cyclooxygenase-2, PHS II, Prostaglandin H2 synthase 2, Prostaglandin-endoperoxide synthase 2,
  • Conjugate/tag Unconjugated
  • Catalog Number TA385085
  • Isotype IgG
  • Storage format 50mM Tris-Glycine(pH 7.4), 0.15M NaCl, 40% Glycerol, 0.01% Sodium azide and 0.05% BSA
  • Clonality Monoclonal
  • Accession numbers P35354
  • Gene target PTGS2
  • Clone R04
  • Datasheet https://cdn.origene.com/datasheet/ta385085.pdf
  • MSDS https://cdn.origene.com/sds/ta385085.pdf
  • Shipping handling time 28 days

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