Origene

BID Mouse Monoclonal Antibody (Biotin conjugated) [Clone ID: OTI1G1]

Supplier Origene

$551.45 / 100 ul
Applications : Western Blot
Reactivity : Human
Conjugate/Tag : Biotin
Host: : Mouse

This gene encodes a death agonist that heterodimerizes with either agonist BAX or antagonist BCL2. The encoded protein is a member of the BCL-2 family of cell death regulators. It is a mediator of mitochondrial damage induced by caspase-8 (CASP8); CASP8 cleaves this encoded protein, and the COOH-terminal part translocates to mitochondria where it triggers cytochrome c release. Multiple alternatively spliced transcript variants have been found, but the full-length nature of some variants has not been defined. [provided by RefSeq, Jul 2008]

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