APPBP1 (NAE1) Rabbit Monoclonal Antibody [Clone ID: R03-1A7]

Supplier Origene

$413.25 / 100 ul
Applications : Western Blot / Immunoprecipitation
Reactivity : Human
Conjugate/Tag : Unconjugated
Host: : Rabbit

Swiss-Prot Acc.Q13564.Regulatory subunit of the dimeric UBA3-NAE1 E1 enzyme. E1 activates NEDD8 by first adenylating its C-terminal glycine residue with ATP, thereafter linking this residue to the side chain of the catalytic cysteine, yielding a NEDD8-UBA3 thioester and free AMP. E1 finally transfers NEDD8 to the catalytic cysteine of UBE2M. Necessary for cell cycle progression through the S-M checkpoint. Overexpression of NAE1 causes apoptosis through deregulation of NEDD8 conjugation.

  • Protein names NEDD8-activating enzyme E1 regulatory subunit
  • Protein alternative names Amyloid beta precursor protein-binding protein 1, 59 kDa, Amyloid protein-binding protein 1, Proto-oncogene protein 1, ,
  • Conjugate/tag Unconjugated
  • Catalog Number TA384833
  • Isotype IgG
  • Storage format 50mM Tris-Glycine(pH 7.4), 0.15M NaCl, 40% Glycerol, 0.01% Sodium azide and 0.05% BSA
  • Clonality Monoclonal
  • Accession numbers Q13564
  • Gene target NAE1
  • Clone R03
  • Datasheet https://cdn.origene.com/datasheet/ta384833.pdf
  • MSDS https://cdn.origene.com/sds/ta384833.pdf
  • Shipping handling time 28 days

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