Anti-TNF Receptor II (Hu,Ms,Rt) from Rabbit (pAb) – unconj.

Supplier Dianova

$418.66 / 200 ul
Applications : ELISA / Western Blot / Immunofluorescence / Immunocytochemistry
Reactivity : Human / Rat / Mouse
Conjugate/Tag : unconjugated
Host: : Rabbit

Receptor with high affinity for TNFSF2/TNF-alpha and approximately 5-fold lower affinity for homotrimeric TNFSF1/lymphotoxin-alpha. The TRAF1/TRAF2 complex recruits the apoptotic suppressors BIRC2 and BIRC3 to TNFRSF1B/TNFR2. This receptor mediates most of the metabolic effects of TNF-alpha. Isoform 2 blocks TNF-alpha-induced apoptosis, which suggests that it regulates TNF-alpha function by antagonizing its biological activity.
TNF Receptor II Antibody detects endogenous levels of total TNF Receptor II

  • Protein names Tumor necrosis factor receptor superfamily member 1B
  • Protein alternative names Tumor necrosis factor receptor 2, Tumor necrosis factor receptor type II, p75, p80 TNF-alpha receptor,
  • Conjugate/tag unconjugated
  • Antibody type Primary Antibody
  • Catalog Number AF5470-02
  • Clonality Polyclonal
  • Accession numbers P20333
  • Gene target TNFRSF1B
  • Datasheet

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