Anti-TNF-R2 (Hu,Ms,Rt) from Rabbit (pAb) – unconj.
Supplier Dianova
Applications
:
ELISA
/
Western Blot
/
Immunofluorescence
/
Immunocytochemistry
Reactivity
:
Human
/
Rat
/
Mouse
Conjugate/Tag
:
unconjugated
Host:
:
Rabbit
Receptor with high affinity for TNFSF2/TNF-alpha and approximately 5-fold lower affinity for homotrimeric TNFSF1/lymphotoxin-alpha. The TRAF1/TRAF2 complex recruits the apoptotic suppressors BIRC2 and BIRC3 to TNFRSF1B/TNFR2. This receptor mediates most of the metabolic effects of TNF-alpha. Isoform 2 blocks TNF-alpha-induced apoptosis, which suggests that it regulates TNF-alpha function by antagonizing its biological activity.
TNF-R2 antibody detects endogenous levels of total TNF-R2
- Protein names Tumor necrosis factor receptor superfamily member 1B
- Protein alternative names Tumor necrosis factor receptor 2, Tumor necrosis factor receptor type II, p75, p80 TNF-alpha receptor,
- Conjugate/tag unconjugated
- Antibody type Primary Antibody
- Catalog Number AF0364-02
- Clonality Polyclonal
- Accession numbers P20333
- Gene target TNFRSF1B
- Datasheet http://www.affbiotech.com/goods-270.html