Anti-TNF-beta (Hu) from Rabbit (Clone: pAb) – unconj.

Supplier Dianova

$584.81 / 100 ug
Applications : ELISA / Western Blot
Reactivity : Human
Conjugate/Tag : unconjugated
Host: : Rabbit

TNF-beta, also known as lymphotoxin-alpha (LTalpha) and TNF-alpha are two structurally and functionally related proteins that bind to the same cell surface receptors (TNF RI and TNF RII) and produce a vast range of similar, but not identical effects. Mature TNF-beta/LTalpha and TNF-alpha share approximately 35% protein sequence homology, and the biologically active secreted forms of both proteins are trimers. Human and mouse TNF-beta/LTalpha share approximately 74% homology in their amino acid sequence and exhibit cross-species activity. Soluble TNF-beta/LTalpha is a homotrimer in solution. Secreted TNF-beta/LTalpha also complexes with the membrane associated LTbeta/TNFSF3 to generate two types of heterotrimers, LTalpha1/beta2 and LTalpha2/beta1.

  • Conjugate/tag unconjugated
  • Antibody type Primary Antibody
  • Catalog Number CYT-026677
  • Clonality Polyclonal

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