ALDH3A2 Monoclonal Antibody (OTI1D1), TrueMAB™

Supplier Thermo fisher

$416.51 / 100 ul
Applications : Western Blot
Reactivity : Human
Conjugate/Tag : Unconjugated
Host: : Mouse

Target Information

Aldh3A2 is a member of the aldehyde dehydrogenase superfamily, a group of NAD(P)(+)-dependent enzymes that catalyze the oxidation of a wide spectrum of aliphatic and aromatic aldehydes. Aldehyde dehydrogenase enzymes are thought to play a major role in the detoxification of aldehydes generated by alcohol metabolism and lipid peroxidation. Aldh3A2 catalyzes the oxidation of long-chain aliphatic aldehydes to fatty acids. Mutations in the Aldh3A2 gene cause Sjogren-Larrson syndrome, an inherited neurocutaneous disorder. Patients with this disorder display ichthyosis, mental retardation and spastic diplegia. The pathogenesis of the cutaneous and neurological symptoms is thought to result from abnormal lipid accumulation in the membranes of skin and brain, the formation of aldehyde Schiff base adducts with amine-containing lipids or proteins, or defective eicosanoid metabolism.

  • Protein names Aldehyde dehydrogenase family 3 member A2
  • Protein alternative names Aldehyde dehydrogenase 10, Fatty aldehyde dehydrogenase, Microsomal aldehyde dehydrogenase, ,
  • Immunogen Full length human recombinant protein of human ALDH3A2 produced in HEK293T cell.
  • Conjugate/tag Unconjugated
  • Antibody type Primary Antibody
  • Catalog Number TA503165
  • Isotype IgG2b
  • Storage format PBS with 1% BSA, 50% glycerol
  • Clonality Monoclonal
  • Accession numbers P51648
  • Gene target ALDH3A2
  • Clone OTI1D1
  • Datasheet

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