Adiponectin Monoclonal Antibody (OTI1B2), TrueMAB™
Supplier Thermo fisher
$416.51
/ 100 ul
Target Information
Adiponectin is a protein hormone secreted exclusively by adipocytes that regulates the metabolism of lipids and glucose. Adiponectin has been shown to play a role in various physiological processes including homeostasis and obesity. Decreased levels of adiponectin are associated with obese individuals as well as insulin resistance and hyperinsulinemia (type 2 diabetes). In mice adiponectin has been shown to improve insulin signaling, thus ameliorating insulin resistance. Through activation of AMP kinase and PPAR-alpha, adiponectin can increase fatty acid transport, oxidation, and dissipation in skeletal muscle, leading to a reduction of intramyocellular lipid levels and thus improved insulin signaling.
- Protein names Adiponectin
- Protein alternative names 30 kDa adipocyte complement-related protein, Adipocyte complement-related 30 kDa protein, Adipocyte, C1q and collagen domain-containing protein, Adipose most abundant gene transcript 1 protein, Gelatin-binding protein
- Immunogen Human recombinant protein fragment corresponding to amino acids 19-244 of human ADIPOQ produced in HEK293T cell.
- Conjugate/tag Unconjugated
- Antibody type Primary Antibody
- Catalog Number TA503801
- Isotype IgG1
- Storage format PBS with 1% BSA, 50% glycerol
- Clonality Monoclonal
- Accession numbers Q15848
- Gene target ADIPOQ
- Clone OTI1B2
- Datasheet https://cdn.origene.com/datasheet/ta503801.pdf
