All HSPA1A Heat shock 70 kDa protein 1A antibodies

HSPA1A (Heat shock 70 kDa protein 1A) is a molecular chaperone that regulates the survival of stressed and cancer cells. It is also known as HSP70-1 or HSP72. HSPA1A is a member of the heat shock protein 70 family and is encoded by the HSPA1A gene.
HSPA1A is a cytosolic protein that is induced by various stressors such as heat shock, oxidative stress, and heavy metals. It plays an important role in protein folding and degradation, as well as in the regulation of apoptosis. HSPA1A has also been shown to be involved in the immune response.
Antibodies that detect HSPA1A can be used in several scientific applications, including Western Blot, Immunohistochemistry, Immunocytochemistry, ELISA and Flow Cytometry. Rabbit polyclonal anti- HSPA1A antibody is used to tag plasma circulating 70 kDa heat shock protein for detection and quantitation by immunocytochemical and immunohistochemical (IHC) techniques.
Inhibition of HSPA1A has been shown to significantly inhibit the malignant progression of lung cancer with ARID2 deficiency. Together, these findings establish ARID2 as an important tumor suppressor in LUADs with novel mechanistic insights, and further identify HSPA1A as a potential therapeutic target in ARID2-deficient LUADs.

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