All CTNNB1 Catenin beta-1 antibodies

Catenin beta-1 (CTNNB1) is a protein that plays a crucial role in the Wnt signaling pathway. It is also known as beta-catenin and is encoded by the CTNNB1 gene in humans. CTNNB1 is a transcriptional co-activator that interacts with T-cell factor/lymphoid enhancer factor (TCF/LEF) family members to activate Wnt target genes.
CTNNB1 is involved in cell adhesion and cell signaling. It is also involved in the regulation of cell growth and differentiation. CTNNB1 is a key component of the adherens junctions that are responsible for cell-cell adhesion.
Antibodies targeting CTNNB1 are used in research to study the protein's function and role in cancer. For example, an engineered antibody fragment targeting mutant β-catenin via major histocompatibility complex I neoantigen presentation was developed to study mutations in CTNNB1, which are common in colon and liver cancers.

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